Ibutamoren (MK-677)


CLASSIFICATION: Growth Hormone Secretagogue
DOSAGE: 15mg/Pill

Categories: ,


MK 677, known as a potent growth hormone (GH) secretagogue, imitates GH’s stimulating action on ghrelin—an endogenous hormone. Explored extensively over the last decade for addressing low IGF-1 levels, growth hormone deficiencies, and osteoporosis, MK 677, or Ibutamoren, emerges as a safer and more economical alternative to growth hormone.


Ibutamoren elevates the release of hormones, including growth hormone and IGF-1, without impacting cortisol levels. This surge in IGF-1 and growth hormone yields various benefits, particularly in enhancing endurance, promoting fat loss, and facilitating muscle mass gain. Additionally, it contributes to combating obesity by modifying body fat metabolism.

Studies and Medical Applications:

Research demonstrates that Ibutamoren augments both muscle mass and bone mineral density while impeding the accumulation of body fat. Notably, subjects experiencing caloric deficits managed to gain lean muscle mass. Ibutamoren presents itself as a promising solution for athletes aiming to achieve:

  1. Fat loss
  2. Muscle gain
  3. Injury healing and bone strengthening

Furthermore, it aids in improving endurance, mood, sleep, and overall health, delivering the benefits of heightened growth hormone and IGF-1 without the hefty costs and side effects associated with HGH.


Ibutamoren can be strategically stacked for diverse benefits:

  1. Endurance: Pairing Ibutamoren with 20 mg of cardarine daily forms a powerful endurance stack, advantageous for endurance athletes seeking to outperform their competition.
  2. Fat Loss: Combining Ibutamoren with andarine and cardarine creates an effective fat-burning triple stack, preventing fat gain and combating obesity.
  3. Mass Gain: Stacking Ibutamoren with LGD and anabolic steroids enables mass gain without the apprehension of spiking body fat measurements.
  4. Overall Health: Ibutamoren, when combined with N2guard, Ostarine, and HCGenerate ES, contributes to an enhanced mood, improved sleep, regulated cholesterol levels, injury healing, and immune system support—a perfect stack for those prioritizing overall health without resorting to anabolic steroids.

Side Effects:

While Ibutamoren has fewer side effects than growth hormone, an increase in appetite is noticeable, often manifesting as cravings for specific foods like red meat or carbs. Water retention, a rare side effect, can be managed with dietary adjustments or diuretics for experienced users. Importantly, Ibutamoren keeps prolactin and cortisol inhibited, assuring users of its safety. The inclusion of HCGenerate ES as a preventive measure can address any concerns related to prolactin.

Half-life, Usage, and Dosage:

With a robust 24-hour half-life, Ibutamoren requires once-daily dosing. Administered orally in the form of a research chemical liquid, it is recommended to squirt it into the mouth on an empty stomach upon waking up, followed by the ingestion of 25 mg daily. Dosages may vary, ranging from 5 mg to 50 mg based on individual preferences and requirements.

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